Impacto del empleo de paneles sindrómicos moleculares en el manejo de pacientes atendidos en el Hospital General del Sur de Quito

Abstract

The identification of causative agents of pulmonary diseases is currently of great importance due to its short response time, its high sensitivity and specificity for the detection of the causative agent of the disease, thus, molecular diagnosis has become a fundamental part for the detection of infectious diseases. With the help of this technique, results and resistance to different types of antibiotics can be obtained in a short time and thus the treating physician can use an appropriate therapeutic alternative for such disease. (Kalil, 2016). Respiratory pathogens can cause acute and severe diseases. Being so the most severe cases are children, elderly and immunocompromised patients. Most respiratory symptoms are similar. For this reason, it is not possible to make a diagnosis based only on clinical manifestations (Behar, 2003). The infectious disease diagnostic area of the Hospital del IESS Quito Sur implemented automated equipment (Phoenix, BD FilmArray M50), which helps in the early diagnosis of the causative agent of respiratory disease. The samples (sputum, tracheal exudate, bronchoalveolar lavage) submitted for analysis for the diagnosis of these are based on traditional culture (blood agar, MacConkey agar, among others), biochemical tests (catalase, citrate, etc.) or stains (Ziehl Nielsen, Gram, etc.) are also performed (GermánBoua, 2011). This study analyzes the importance of the use of molecular panels, such as pneumonia panel (PN) and others, the impact of the use of such panels in the antibiotic therapy provided to patients with respiratory diseases, as well as variables such as (response time, antibiotic administered, how long the treatment lasted, days of hospitalization, how many patients required ICU, area requesting, antibiotic resistance, outcome) will be analyzed.