Exposición a sustancias antineoplásicas (citostáticos) y efectos adversos en la salud del personal sanitario de una clínica privada en Quito

Abstract

Objectives: To evaluate the adverse health effects in health personnel working in the Oncology area of Private Clinic of Quito, exposed to antineoplastic drugs at manipulate, prepare and administer in the treatment of cancer, to prevent occupational hazards. Method: Cross-sectional, prospective, descriptive, non-experimental observational study. The data will be collected during the year 2021, in a population of 14 health workers who perform reconstitution and dilution of oncological formulas, as well as the personnel administering the chemotherapy in the Oncology service. Results: With this proposal it is expected to obtain the results acute and chronic clinical manifestations in all personnel working in the Oncology area obtained from the validated survey, in addition to reflecting results in biomarker studies both in urine and blood that are linked to alterations in sexual reproduction such as infertility, miscarriages, etc., as well as hematological problems with cancer, genotoxicity and teratogenicity in personnel. Implications: The proposal may provide more realistic information on health effects in the health personnel of the Oncology area in our country and establish surveillance programs for this activity and avoid the risks generated by not having a strict control, it will also help to generate a standardization of management of cytostatic agents.