Plasma rico en factores de crecimiento para el manejo de las úlceras del pie diabético. Un metaanálisis

Abstract

The increase in patients who register Diabetes Mellitus is increasingly wide, this entails difficulties not only at the individual level, but also political and social in terms of new forms of clinical care. In particular, these patients show alterations or ulcers, many times difficult to heal. For this reason, it is essential to have a scientifically validated study that allows to know how the research has been carried out to date on the treatments associated with the use of Plasma Rich in growth factors for the management of diabetic foot ulcers. For this, a systematic review of the literature and a meta-analysis were carried out that followed the guidelines suggested by the PRISMA methodology. Originally 105 articles were identified, but after screening, 10 that met the inclusion criteria were included. Finally, after analyzing the results, it is concluded that the application of PRP as a complementary treatment decreases the healing time of diabetic foot ulcers and, in addition, reduces the risk of superinfection by preventing the wound from remaining exposed for a longer time, offering advantages over conventional treatment.