Please use this identifier to cite or link to this item:
http://repositorio.uisek.edu.ec/handle/123456789/4989
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | Arisqueta Herranz, Lino | - |
dc.contributor.author | Cañizares Villalba, Sebastián Alejandro | - |
dc.date.accessioned | 2023-04-17T17:03:03Z | - |
dc.date.available | 2023-04-17T17:03:03Z | - |
dc.date.issued | 2023-04 | - |
dc.identifier.citation | CT-BIO C138ob/2023 | es |
dc.identifier.uri | http://repositorio.uisek.edu.ec/handle/123456789/4989 | - |
dc.description | This article addresses the issue of cardiovascular diseases (CVDs), which continue to be the leading cause of death worldwide. The research hypothesis focuses on whether microbial-derived enzymes with thrombolytic and/or fibrinolytic properties can be exploited for the treatment of these diseases. Selective culture media for protease-producing bacteria were used, and assays for gelatinases and caseinases were performed. Non-specific enzymatic activity was measured using the Folin-Ciocalteu method. Subsequently, tests were carried out with blood clots, identifying that B. megaterium and S. liquefaciens exhibit such activities. It is concluded that B. Megaterium is a promising organism for producing enzymes capable of dissolving thrombi | es |
dc.description.abstract | Este artículo aborda la problemática de las enfermedades cardiovasculares (ECVs), las cuales continúan siendo la principal causa de muerte a nivel mundial. La hipótesis de la investigación se enfoca en si es posible aprovechar enzimas de origen microbiano con propiedades trombolíticas y/o fibrinolíticas para el tratamiento de este tipo de enfermedades. Se utilizó medios de cultivo selectivos para bacterias productoras de proteasas y se realizaron ensayos para gelatinasas y caseinasas. La actividad enzimática no específica se midió mediante el método con el reactivo de FolinCiocalteu. Posteriormente, se realizaron ensayos con coágulos de sangre, identificando que B. megaterium y S. liquefaciens presentan dichas actividades. Se concluye que B. megaterium es un organismo prometedor para producir enzimas capaces de disolver trombos. | es |
dc.description.sponsorship | Uisek | es |
dc.language.iso | spa | es |
dc.publisher | Universidad Internacional Sek | es |
dc.rights | openAccess | es |
dc.subject | BIOTECNOLOGÍA | es |
dc.subject | ENFERMEDADES CARDIOVASCULARES | es |
dc.subject | ENZIMAS MICROBIANAS | es |
dc.subject | TROMBOLÍTICO | es |
dc.subject | FIBRINOLÍTICO | es |
dc.title | Obtención y caracterización de enzimas trombolíticas y/o fibrinolíticas a partir de microorganismos del suelo | es |
dc.type | info:eu-repo/semantics/article | es |
Appears in Collections: | Biotecnología |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Cañizares Villalba Sebastián Alejandro.pdf | 1.29 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.